High time to omit oxygen therapy in ST elevation myocardial infarction

High time to omit oxygen therapy in ST elevation myocardial infarction

Supplemental oxygen (O2) therapy in patients with chest pain has been a cornerstone in the treatment of suspected myocardial infarction (MI). Recent randomized controlled trials have, however, shown that supplemental O2 therapy has no positive nor negative effects on cardiovascular functions, mortality, morbidity or pain in normoxic patients with suspected MI and foremost patients with…

Pre-hospital prediction of transmural myocardial infarction and the need of acute coronary reperfusion by an artificial neural network compared to real-time prediction by a cardiac care unit physician
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Pre-hospital prediction of transmural myocardial infarction and the need of acute coronary reperfusion by an artificial neural network compared to real-time prediction by a cardiac care unit physician

Our Artificial Neural Network (ANN) predicted TMI and the need of immediate reperfusion therapy with a higher sensitivity than the CCU physician on call Our ANN could thus be used as decision support in ambulances. The value would primarily be in ruling out TMI and the need of immediate reperfusion When the ANN suggests immediate…

Ischemic QRS prolongation as a biomarker of myocardial injury in STEMI patients

Ischemic QRS prolongation as a biomarker of myocardial injury in STEMI patients

Background Patients with acute coronary occlusion (ACO) may not only have ischemia‐related ST‐segment changes but also changes in the QRS complex. It has recently been shown in dogs that a greater ischemic QRS prolongation (IQP) during ACO is related to lower collateral flow. This suggests that greater IQP could indicate more severe ischemia and thereby…

A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients
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A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients

If a 0h/1h protocol implemented in routine care can rapidly identify a large proportion of chest pain patients suitable for early discharge, with no need for further cardiac testing, this may reduce ED and hospital crowding, objective testing, health care costs and will benefit both patients and the health care system.

A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients
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A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients

Background In emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety…

The West’s Role in the Shah’s Overthrow
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The West’s Role in the Shah’s Overthrow

On January 16, 1979, Shah Mohammed Reza Pahlavi, who had ruled Iran for nearly thirty-eight years, left the country in the face of a nationwide popular revolution—never to return. Shortly after his departure, it became known that the deposed monarch suffered from advanced cancer, and on July 27, 1980, he passed away in Cairo, at…