Association between endostatin and mortality in patients with acute dyspnoea, with or without congestive heart failure: a single-centre, prospective, observational study

Association between endostatin and mortality in patients with acute dyspnoea, with or without congestive heart failure: a single-centre, prospective, observational study

Objective: The aim of this study was to assess associations between endostatin levels and short-term mortality in unsorted acute hospitalised dyspnoea patients with or without congestive heart failure (CHF), adjusted for common cardiovascular risk factors. Design, setting and participants In this prospective observational study, 723 hospitalised patients who visited the emergency department at Skåne University…

Healthcare efforts for the “invisible” with opioid problems must improve.

Healthcare efforts for the “invisible” with opioid problems must improve.

Despite the fact that the majority of those who die from opioid overdoses have been in contact with healthcare, social services, or the justice system, a new analysis shows that a large group – nearly half – lacks significant care connections related to their drug problems. To strengthen preventive efforts against overdoses, a change in…

A novel interpretable deep learning model for diagnosis in emergency department dyspnoea patients based on complete data from an entire health care system

A novel interpretable deep learning model for diagnosis in emergency department dyspnoea patients based on complete data from an entire health care system

Background Dyspnoea is one of the emergency department’s (ED) most common and deadly chief complaints, but frequently misdiagnosed and mistreated. We aimed to design a diagnostic decision support which classifies dyspnoeic ED visits into acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), pneumonia and “other diagnoses” by using deep learning and complete,…

Effectiveness and Safety of the ESC‐TROP (European Society of Cardiology 0h/1h Troponin Rule‐Out Protocol) Trial

Effectiveness and Safety of the ESC‐TROP (European Society of Cardiology 0h/1h Troponin Rule‐Out Protocol) Trial

Background: European guidelines recommend the use of a 0h/1h hs‐cTn (high‐sensitivity cardiac troponin) protocol in patients with acute chest pain. We aimed to determine the performance of this protocol in routine care when supplemented with patient history and ECG and a recommendation to refrain from noninvasive testing in low‐risk patients. Methods and Results: This was…

Patterns of care contacts in the final year of life among opioid overdose fatalities in southern Sweden: a latent class analysis
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Patterns of care contacts in the final year of life among opioid overdose fatalities in southern Sweden: a latent class analysis

Background Understanding the heterogeneity of opioid overdose fatalities is critical to developing effective preventive interventions. This study examines patterns of care contacts among people who subsequently died from opioid overdose. The aim was to identify distinct groups of deceased individuals, based on their contacts with different care agencies in their last year of life. Methods…

A Forensic Epidemiological Perspective on Single Stab Injuries to the Trunk in Surviving Assault Victims [German]
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A Forensic Epidemiological Perspective on Single Stab Injuries to the Trunk in Surviving Assault Victims [German]

This study examines whether injury characteristics in surviving victims of assaults with single stab wounds to the trunk are comparable to those observed in homicide cases. Using data from the Swedish National Board of Forensic Medicine for assault cases (2016-2017) and forensic autopsy data for homicides (2010-2021), a total of 152 assault survivors were compared…

Lethal injuries in single stabs to the trunk – A study on homicides and suicides in Sweden
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Lethal injuries in single stabs to the trunk – A study on homicides and suicides in Sweden

Introduction Homicides using knives or other sharp objects are the most common type of homicide in Europe, and the second most common type of homicide worldwide. In contrast, suicides using sharp objects are rarer, constituting only a few per cent of all suicides in western countries. We investigated single stab injuries to the trunk in…

How does an AI diagnose dyspnoea in ED triage without human guidance?

How does an AI diagnose dyspnoea in ED triage without human guidance?

The study aimed to improve ED triage for dyspnoeic adult patients using AI, analyzing data from two Swedish EDs. Key predictive variables prioritized by the AI included previous heart failure diagnosis, atrial fibrillation on ECG, COPD complaints, and specific medications. Surprisingly, veterinary medication intake showed predictive value, while traditional indicators like vital signs and sex…

Male-on-Male Sexual Homicide: A Systematic Review
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Male-on-Male Sexual Homicide: A Systematic Review

Sexual homicide has been heavily studied, yet the majority of the studies have focused on male offenders killing female victims (MFSH), thereby neglecting male-on-male sexual homicide (MMSH), i.e., instances where an adult male offender murders an adult male victim. To summarize the current understanding of this crime type, a systematic review was conducted. The objective…