Effectiveness and Safety of the ESC‐TROP (European Society of Cardiology 0h/1h Troponin Rule‐Out Protocol) Trial

Effectiveness and Safety of the ESC‐TROP (European Society of Cardiology 0h/1h Troponin Rule‐Out Protocol) Trial

Background: European guidelines recommend the use of a 0h/1h hs‐cTn (high‐sensitivity cardiac troponin) protocol in patients with acute chest pain. We aimed to determine the performance of this protocol in routine care when supplemented with patient history and ECG and a recommendation to refrain from noninvasive testing in low‐risk patients. Methods and Results: This was…

Patterns of care contacts in the final year of life among opioid overdose fatalities in southern Sweden: a latent class analysis
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Patterns of care contacts in the final year of life among opioid overdose fatalities in southern Sweden: a latent class analysis

Background Understanding the heterogeneity of opioid overdose fatalities is critical to developing effective preventive interventions. This study examines patterns of care contacts among people who subsequently died from opioid overdose. The aim was to identify distinct groups of deceased individuals, based on their contacts with different care agencies in their last year of life. Methods…

A Forensic Epidemiological Perspective on Single Stab Injuries to the Trunk in Surviving Assault Victims [German]
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A Forensic Epidemiological Perspective on Single Stab Injuries to the Trunk in Surviving Assault Victims [German]

This study examines whether injury characteristics in surviving victims of assaults with single stab wounds to the trunk are comparable to those observed in homicide cases. Using data from the Swedish National Board of Forensic Medicine for assault cases (2016-2017) and forensic autopsy data for homicides (2010-2021), a total of 152 assault survivors were compared…

Lethal injuries in single stabs to the trunk – A study on homicides and suicides in Sweden
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Lethal injuries in single stabs to the trunk – A study on homicides and suicides in Sweden

Introduction Homicides using knives or other sharp objects are the most common type of homicide in Europe, and the second most common type of homicide worldwide. In contrast, suicides using sharp objects are rarer, constituting only a few per cent of all suicides in western countries. We investigated single stab injuries to the trunk in…

How does an AI diagnose dyspnoea in ED triage without human guidance?

How does an AI diagnose dyspnoea in ED triage without human guidance?

The study aimed to improve ED triage for dyspnoeic adult patients using AI, analyzing data from two Swedish EDs. Key predictive variables prioritized by the AI included previous heart failure diagnosis, atrial fibrillation on ECG, COPD complaints, and specific medications. Surprisingly, veterinary medication intake showed predictive value, while traditional indicators like vital signs and sex…

Male-on-Male Sexual Homicide: A Systematic Review
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Male-on-Male Sexual Homicide: A Systematic Review

Sexual homicide has been heavily studied, yet the majority of the studies have focused on male offenders killing female victims (MFSH), thereby neglecting male-on-male sexual homicide (MMSH), i.e., instances where an adult male offender murders an adult male victim. To summarize the current understanding of this crime type, a systematic review was conducted. The objective…

Relationships between Charlson comorbidity index associated biomarkers and outcomes among participants in the Malmö diet and cancer study

Relationships between Charlson comorbidity index associated biomarkers and outcomes among participants in the Malmö diet and cancer study

Introduction The aim was to evaluate two biomarker scores trained to identify comorbidity burden in the prediction of specified chronic morbidities, and mortality in the general population. Methods Cardiovascular biomarkers were measured in the cardiovascular cohort of the Malmö Diet and Cancer Study. A score of 19 biomarkers associated with Charlson Comorbidity Index (CCI) was…

Contractility, ventriculoarterial coupling, and stroke work after acute myocardial infarction using CMR-derived pressure-volume loop data

Contractility, ventriculoarterial coupling, and stroke work after acute myocardial infarction using CMR-derived pressure-volume loop data

Background: Noninvasive left ventricular (LV) pressure-volume (PV) loops derived by cardiac magnetic resonance (CMR) have recently been shown to enable characterization of cardiac hemodynamics. Thus, such PV loops could potentially provide additional diagnostic information such as contractility, arterial elastance (Ea) and stroke work (SW) currently not available in clinical routine. This study sought to investigate…

Prognostic utility and characterization of left ventricular hypertrophy using global thickness

Prognostic utility and characterization of left ventricular hypertrophy using global thickness

Cardiovascular magnetic resonance (CMR) can accurately measure left ventricular (LV) mass, and several measures related to LV wall thickness exist. We hypothesized that prognosis can be used to select an optimal measure of wall thickness for characterizing LV hypertrophy. Subjects having undergone CMR were studied (cardiac patients, n = 2543; healthy volunteers, n = 100). A new measure, global…