Effectiveness and Safety of the European Society of Cardiology 0-/1-h Troponin Rule-Out Protocol: The Design of the ESC-TROP Multicenter Implementation Study

Effectiveness and Safety of the European Society of Cardiology 0-/1-h Troponin Rule-Out Protocol: The Design of the ESC-TROP Multicenter Implementation Study

Chest pain is one of the most common complaints at the emergency department (ED), and it is commonly the perceived likelihood of acute coronary syndrome (ACS) that drives management. Guidelines from the European Society of Cardiology (ESC) recommend the use of a 0-/1-h high-sensitivity cardiac troponin T (hs-cTnT) protocol to rule out or in ACS,…

Deadly violence in Sweden: Profiling offenders through a latent class analysis
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Deadly violence in Sweden: Profiling offenders through a latent class analysis

Background Sweden has in recent years witnessed increasing rates of firearm-related violence and homicide, which has contributed to increased rates of deadly violence. Attempts to profile offenders committing such crimes are of major importance, because such efforts may contribute to better preventive measures. We therefore aimed to study the characteristics of individuals convicted and/or suspected…

Corona is a Threat to Sweden´s National Security [Swedish]
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Corona is a Threat to Sweden´s National Security [Swedish]

An infectious disease such as covid-19 threatens both human security and national security. A political instability as a result of poor economy, reduced confidence in social institutions, general demoralization and fear, can also have consequences that directly threaten Sweden’s security, writes Ardavan Khoshnood, physician and criminologist.

Oxygen therapy in patients with ST elevation myocardial infarction based on the culprit vessel: results from the randomized controlled SOCCER trial

Oxygen therapy in patients with ST elevation myocardial infarction based on the culprit vessel: results from the randomized controlled SOCCER trial

Background Oxygen (O2) treatment has been a cornerstone in the treatment of patients with myocardial infarction. Recent studies, however, state that supplemental O2 therapy may have no effect or harmful effects in these patients. The aim of this study was thus to evaluate the effect of O2 therapy in patients with ST Elevation Myocardial Infarction…

Electrocardiographic changes in the differentiation of ischemic and non-ischemic ST elevation

Electrocardiographic changes in the differentiation of ischemic and non-ischemic ST elevation

Objectives  Pericarditis, takotsubo cardiomyopathy and early repolarization syndrome (ERS) are well-known to mimic ST elevation myocardial infarction (STEMI). We aimed to study whether ECG findings of reciprocal ST depression, PR depression, ST-segment convexity or terminal QRS distortion can discriminate between ST elevation due to ischemia and non-ischemic conditions. Design  Eighty-five patients with STEMI and 94…

Diagnostic accuracy of troponin T measured ≥6h after symptom onset for ruling out myocardial infarction

Diagnostic accuracy of troponin T measured ≥6h after symptom onset for ruling out myocardial infarction

Objectives Guidelines recommend a single high-sensitivity cardiac troponin T (hs-cTnT) ≤14 ng/L measured ≥6 h after chest pain onset combined with a GRACE score <140 and the patient being pain-free for ruling out myocardial infarction (MI). There is however little data on the performance of this strategy. We therefore aimed to evaluate the diagnostic accuracy of a…

Diagnostic Accuracy of History and Physical Examination for Predicting Major Adverse Cardiac Events Within 30 Days in Patients With Acute Chest Pain

Diagnostic Accuracy of History and Physical Examination for Predicting Major Adverse Cardiac Events Within 30 Days in Patients With Acute Chest Pain

Background The cornerstones in the assessment of emergency department (ED) patients with suspected acute coronary syndrome (ACS) are patient history and physical examination, electrocardiogram, and cardiac troponins. Although there are several prior studies on this subject, they have in some cases produced inconsistent results. Objective The aim of this study was to evaluate the diagnostic…

Electrocardiographic changes beyond ST elevation in the differentiation of ischemic and non-ischemic ST elevation in patients with chest pain
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Electrocardiographic changes beyond ST elevation in the differentiation of ischemic and non-ischemic ST elevation in patients with chest pain

Reciprocal ST depression, PR depression in the chest leads and terminal QRS distortion may improve detection of true STEMI. Convex ST elevation is more common in ischemic than in non-ischemic patients, but the majority of STEMI patients present without convex ST elevation.