Pre-hospital prediction of transmural myocardial infarction and the need of acute coronary reperfusion by an artificial neural network compared to real-time prediction by a cardiac care unit physician
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Pre-hospital prediction of transmural myocardial infarction and the need of acute coronary reperfusion by an artificial neural network compared to real-time prediction by a cardiac care unit physician

Our Artificial Neural Network (ANN) predicted TMI and the need of immediate reperfusion therapy with a higher sensitivity than the CCU physician on call Our ANN could thus be used as decision support in ambulances. The value would primarily be in ruling out TMI and the need of immediate reperfusion When the ANN suggests immediate…

Ischemic QRS prolongation as a biomarker of myocardial injury in STEMI patients

Ischemic QRS prolongation as a biomarker of myocardial injury in STEMI patients

Background Patients with acute coronary occlusion (ACO) may not only have ischemia‐related ST‐segment changes but also changes in the QRS complex. It has recently been shown in dogs that a greater ischemic QRS prolongation (IQP) during ACO is related to lower collateral flow. This suggests that greater IQP could indicate more severe ischemia and thereby…

A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients
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A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients

If a 0h/1h protocol implemented in routine care can rapidly identify a large proportion of chest pain patients suitable for early discharge, with no need for further cardiac testing, this may reduce ED and hospital crowding, objective testing, health care costs and will benefit both patients and the health care system.

A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients
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A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients

Background In emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety…

Chest-lead ST­J amplitudes using arm electrodes as Reference instead of the Wilson central terminal in smartphone ECG applications: Influence on ST-elevation myocardial infarction criteria fulfillment

Chest-lead ST­J amplitudes using arm electrodes as Reference instead of the Wilson central terminal in smartphone ECG applications: Influence on ST-elevation myocardial infarction criteria fulfillment

Background “Smartphone 12-lead ECG” for the assessment of acute myocardial ischemia has recently been introduced. In the smartphone 12-lead ECG either the right or the left arm can be used as reference for the chest electrodes instead of the Wilson central terminal. These leads are labeled “CR leads” or “CL leads.” We aimed to compare…

Left ventricular global wall thickness is easily calculated, detects and characterizes hypertrophy, and has prognostic utility
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Left ventricular global wall thickness is easily calculated, detects and characterizes hypertrophy, and has prognostic utility

Background Cardiovascular magnetic resonance (CMR) can be used to measure left ventricular end-diastolic volume (LVEDV) and left ventricular mass (LVM). However, there is currently no good way to measure the normality of LVM in relation to a given LVEDV. We hypothesized that a simple measure of left ventricular global wall thickness (GWT) would be accurate,…

Diagnostic Accuracy of the Electrocardiographic Decision Support – Myocardial Ischaemia (EDS-MI) Algorithm in Detection of Acute Coronary Occlusion

Diagnostic Accuracy of the Electrocardiographic Decision Support – Myocardial Ischaemia (EDS-MI) Algorithm in Detection of Acute Coronary Occlusion

Electrocardiographic Decision Support – Myocardial Ischaemia (EDS-MI) is a graphical decision support for detection and localization of acute transmural ischaemia. A recent study indicated that EDS-MI performs well for detection of acute transmural ischaemia. However, its performance has not been tested in patients with non-ischaemic ST-deviation. We aimed to optimize the diagnostic accuracy of EDS-MI…

Effects of supplemental oxygen therapy in patients with suspected acute myocardial infarction: A meta-analysis of randomized clinical trials

Effects of supplemental oxygen therapy in patients with suspected acute myocardial infarction: A meta-analysis of randomized clinical trials

Background Although oxygen therapy has been used for over a century in the management of patients with suspected acute myocardial infarction (AMI), recent studies have raised concerns around the efficacy and safety of supplemental oxygen in normoxaemic patients. Objective To synthesise the evidence from randomised controlled trials (RCTs) that investigated the effects of supplemental oxygen…