A simplified left ventricular end-diastolic mean wall thickness-to-volume ratio estimated from left ventricular mass and end-diastolic volume distinguishes physiological from pathological hypertrophy
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A simplified left ventricular end-diastolic mean wall thickness-to-volume ratio estimated from left ventricular mass and end-diastolic volume distinguishes physiological from pathological hypertrophy

Left ventricular end-diastolic mean wall thickness (LVEDMWT) can be simply estimated from left ventricular mass and left ventricular end-diastolic volume with high accuracy and precision. Estimated LVEDMWT can in turn be used to calculate thickness-to-volume ratio (TVR) as a new index of relative wall thickness. The maximum TVR found in endurance athletes was lower than…

Effect of oxygen therapy on myocardial salvage in ST elevation myocardial infarction: The randomized SOCCER trial

Effect of oxygen therapy on myocardial salvage in ST elevation myocardial infarction: The randomized SOCCER trial

Objective Recent studies suggest that administration of O2 in patients with acute myocardial infarction may have negative effects. With the use of cardiac MRI (CMR), we evaluated the effects of supplemental O2 in patients with ST elevation myocardial infarction (STEMI) accepted for acute percutaneous coronary intervention (PCI). Materials and methods This study was a randomized-controlled…

Diagnostic Accuracy of High-Sensitivity Cardiac Troponin T at Presentation Combined With History and ECG for Ruling Out Major Adverse Cardiac Events

Diagnostic Accuracy of High-Sensitivity Cardiac Troponin T at Presentation Combined With History and ECG for Ruling Out Major Adverse Cardiac Events

Study objective We evaluate the diagnostic accuracy of a high-sensitivity cardiac troponin T (hs-cTnT) level less than 5 ng/L or less than or equal to 14 ng/L at emergency department (ED) presentation, combined with the emergency physician’s assessment of history and ECG, for ruling out major adverse cardiac events within 30 days. Methods This prospective…

A 1-h Combination Algorithm Allows Fast Rule-Out and Rule-In of Major Adverse Cardiac Events

A 1-h Combination Algorithm Allows Fast Rule-Out and Rule-In of Major Adverse Cardiac Events

Background A 1-h algorithm based on high-sensitivity cardiac troponin T (hs-cTnT) testing at presentation and again 1 h thereafter has been shown to accurately rule out acute myocardial infarction. Objectives The goal of the study was to evaluate the diagnostic accuracy of the 1-h algorithm when supplemented with patient history and an electrocardiogram (ECG) (the…

The SOCCER-study: Effects of Oxygen Therapy on Myocardial Salvage in ST Elevation Myocardial Infarction – A Randomized Trial
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The SOCCER-study: Effects of Oxygen Therapy on Myocardial Salvage in ST Elevation Myocardial Infarction – A Randomized Trial

Our results showing no difference in MSI between the O2 and air groups suggests that supplemental O2 did not affect the efficacy of reperfusion in STEMI patients accepted for acute PCI. These results support the safety of withholding supplemental oxygen in normoxic STEMI patients.

The Death of an Emperor – Mohammad Reza Shah Pahlavi and his Political Cancer
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The Death of an Emperor – Mohammad Reza Shah Pahlavi and his Political Cancer

Mohammad Reza Pahlavi, the Shah of Iran, was toppled in the Islamic Revolution of 1979. A year later he passed away from lymphoma, a disease he had secretly battled for several years, but still it remains unknown exactly when he was diagnosed with cancer, if he was aware of his condition and who close to…