Diagnostic Accuracy of High-Sensitivity Cardiac Troponin T at Presentation Combined With History and ECG for Ruling Out Major Adverse Cardiac Events

Diagnostic Accuracy of High-Sensitivity Cardiac Troponin T at Presentation Combined With History and ECG for Ruling Out Major Adverse Cardiac Events

Study objective We evaluate the diagnostic accuracy of a high-sensitivity cardiac troponin T (hs-cTnT) level less than 5 ng/L or less than or equal to 14 ng/L at emergency department (ED) presentation, combined with the emergency physician’s assessment of history and ECG, for ruling out major adverse cardiac events within 30 days. Methods This prospective…

A 1-h Combination Algorithm Allows Fast Rule-Out and Rule-In of Major Adverse Cardiac Events

A 1-h Combination Algorithm Allows Fast Rule-Out and Rule-In of Major Adverse Cardiac Events

Background A 1-h algorithm based on high-sensitivity cardiac troponin T (hs-cTnT) testing at presentation and again 1 h thereafter has been shown to accurately rule out acute myocardial infarction. Objectives The goal of the study was to evaluate the diagnostic accuracy of the 1-h algorithm when supplemented with patient history and an electrocardiogram (ECG) (the…

The SOCCER-study: Effects of Oxygen Therapy on Myocardial Salvage in ST Elevation Myocardial Infarction – A Randomized Trial
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The SOCCER-study: Effects of Oxygen Therapy on Myocardial Salvage in ST Elevation Myocardial Infarction – A Randomized Trial

Our results showing no difference in MSI between the O2 and air groups suggests that supplemental O2 did not affect the efficacy of reperfusion in STEMI patients accepted for acute PCI. These results support the safety of withholding supplemental oxygen in normoxic STEMI patients.

The Death of an Emperor – Mohammad Reza Shah Pahlavi and his Political Cancer
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The Death of an Emperor – Mohammad Reza Shah Pahlavi and his Political Cancer

Mohammad Reza Pahlavi, the Shah of Iran, was toppled in the Islamic Revolution of 1979. A year later he passed away from lymphoma, a disease he had secretly battled for several years, but still it remains unknown exactly when he was diagnosed with cancer, if he was aware of his condition and who close to…

Skåne Emergency Department Assessment of Patient Load (SEAL)—A Model to Estimate Crowding Based on Workload in Swedish Emergency Departments

Skåne Emergency Department Assessment of Patient Load (SEAL)—A Model to Estimate Crowding Based on Workload in Swedish Emergency Departments

Objectives Emergency department (ED) crowding is an increasing problem in many countries. The purpose of this study was to develop a quantitative model that estimates the degree of crowding based on workload in Swedish EDs. Methods At five different EDs, the head nurse and physician assessed the workload on a scale from 1 to 6…

The effects of oxygen therapy on myocardial salvage in ST elevation myocardial infarction treated with acute percutaneous coronary intervention – The Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion (SOCCER) study

The effects of oxygen therapy on myocardial salvage in ST elevation myocardial infarction treated with acute percutaneous coronary intervention – The Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion (SOCCER) study

Objectives Despite a lack of scientific evidence, oxygen has long been a part of standard treatment for patients with acute myocardial infarction (AMI). However, several studies suggest that oxygen therapy may have negative cardiovascular effects. We here describe a randomized controlled trial, i.e. Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion (SOCCER), aiming to evaluate the…

The effects of oxygen therapy on myocardial salvage in ST elevation myocardial infarction treated with acute percutaneous coronary intervention – The Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion (SOCCER) study
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The effects of oxygen therapy on myocardial salvage in ST elevation myocardial infarction treated with acute percutaneous coronary intervention – The Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion (SOCCER) study

The SOCCER trial addresses a significant knowledge gap in the routine care of patients with AMI. Even though oxygen therapy is part of standard care, oxygen may not be beneficial to these patients, and possibly even harmful. The results of the present and concurrent oxygen trials may thus change international treatment guidelines for patients with…