A simplified left ventricular end-diastolic mean wall thickness-to-volume ratio estimated from left ventricular mass and end-diastolic volume distinguishes physiological from pathological hypertrophy
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A simplified left ventricular end-diastolic mean wall thickness-to-volume ratio estimated from left ventricular mass and end-diastolic volume distinguishes physiological from pathological hypertrophy

Left ventricular end-diastolic mean wall thickness (LVEDMWT) can be simply estimated from left ventricular mass and left ventricular end-diastolic volume with high accuracy and precision. Estimated LVEDMWT can in turn be used to calculate thickness-to-volume ratio (TVR) as a new index of relative wall thickness. The maximum TVR found in endurance athletes was lower than…

The SOCCER-study: Effects of Oxygen Therapy on Myocardial Salvage in ST Elevation Myocardial Infarction – A Randomized Trial
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The SOCCER-study: Effects of Oxygen Therapy on Myocardial Salvage in ST Elevation Myocardial Infarction – A Randomized Trial

Our results showing no difference in MSI between the O2 and air groups suggests that supplemental O2 did not affect the efficacy of reperfusion in STEMI patients accepted for acute PCI. These results support the safety of withholding supplemental oxygen in normoxic STEMI patients.

The effects of oxygen therapy on myocardial salvage in ST elevation myocardial infarction treated with acute percutaneous coronary intervention – The Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion (SOCCER) study
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The effects of oxygen therapy on myocardial salvage in ST elevation myocardial infarction treated with acute percutaneous coronary intervention – The Supplemental Oxygen in Catheterized Coronary Emergency Reperfusion (SOCCER) study

The SOCCER trial addresses a significant knowledge gap in the routine care of patients with AMI. Even though oxygen therapy is part of standard care, oxygen may not be beneficial to these patients, and possibly even harmful. The results of the present and concurrent oxygen trials may thus change international treatment guidelines for patients with…

Circadian presentation patterns and ECGs of men and women with suspected acute coronary syndrome in the emergency department
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Circadian presentation patterns and ECGs of men and women with suspected acute coronary syndrome in the emergency department

Presentation patterns were quite similar for men and women with a large likelihood of Acute Coronary Syndrome (ACS) for those presenting in the morning. This may be related to changes in the thrombolytic activity, platelet aggregability and sympathetic system activation. In patients with ECG signs of ST elevation ACS, the likelihood for ACS was much…